NOVEL SCREENING SYSTEM OF VIRULENT STRAINS FOR THE ESTABLISHMENT OF A MYCOBACTERIUM AVIUM COMPLEX LUNG DISEASE MOUSE MODEL USING WHOLE-GENOME SEQUENCING

ABSTRACT The establishment of animal models reflecting human Mycobacterium avium complex (MAC) lung disease (LD) pathology has the potential to expand our understanding of the disease pathophysiology.However, inducing sustained infection in immunocompetent mice is difficult since MAC generally shows less virulence and higher genetic variability tha

In the title compound, C13H10N2O5S, the N—C bond in the C—SO2—NH—C segment has gauche torsion angles with respect to the S=O bonds.The conformation between the N—H bond and the ortho-nitro group in the sulfonyl benzene napoleon concealer ring is syn.The molecule is twisted at the S—N bond

Symptoms of anhedonia, or deficits in the ability to experience positive affect, are increasingly recognized as an outcome of traumatic stress including in individuals with PTSD.However, little research has investigated negative affective responses to what would normally be considered pleasant events (e.g., receiving a compliment or gift, physical

The relevance of the economic issues discussed in the article is due to the high degree of interest of developed countries in the implementation of innovative projects.A competent approach to the analysis and evaluation of their economic indicators is the guarantee of their success.The article is devoted to the study of the analysis ventilationstej

Graphitic carbon nitride (g-C3N4) has gained significant attention due to its unique physicochemical properties as a metal-free, two-dimensional, carbon-based polymeric fluorescent substance composed of tris-triazine-based patterns with a slight hydrogen content and a carbon-to-nitrogen ratio of 3:4.It forms layered structures like graphite and dem